| node1 | node2 | node1 annotation | node2 annotation | score |
| CCC_00201 | CCC_01520 | Signal transduction histidine kinase. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.794 |
| CCC_00201 | CCC_01521 | Signal transduction histidine kinase. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.794 |
| CCC_00201 | CCC_01907 | Signal transduction histidine kinase. | Pyruvate-flavodoxin oxidoreductase. | 0.677 |
| CCC_00201 | CCC_02187 | Signal transduction histidine kinase. | BarA sensory histidine kinase (VarS GacS). | 0.998 |
| CCC_00201 | CCC_02640 | Signal transduction histidine kinase. | Multi-sensor hybrid histidine kinase. | 0.998 |
| CCC_00201 | CCC_02787 | Signal transduction histidine kinase. | Sensory box histidine kinase/response regulator. | 0.998 |
| CCC_00201 | CCC_03076 | Signal transduction histidine kinase. | Methionyl-tRNA formyltransferase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.854 |
| CCC_00201 | CCC_03560 | Signal transduction histidine kinase. | Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s). | 0.999 |
| CCC_00201 | CCC_03562 | Signal transduction histidine kinase. | Sensory box histidine kinase/response regulator. | 0.997 |
| CCC_00469 | CCC_01520 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.427 |
| CCC_00469 | CCC_01521 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.499 |
| CCC_00469 | CCC_01907 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate-flavodoxin oxidoreductase. | 0.916 |
| CCC_00469 | CCC_02187 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | BarA sensory histidine kinase (VarS GacS). | 0.419 |
| CCC_00469 | CCC_02787 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sensory box histidine kinase/response regulator. | 0.483 |
| CCC_00469 | CCC_03076 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionyl-tRNA formyltransferase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.921 |
| CCC_00469 | CCC_03562 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sensory box histidine kinase/response regulator. | 0.454 |
| CCC_01520 | CCC_00201 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Signal transduction histidine kinase. | 0.794 |
| CCC_01520 | CCC_00469 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.427 |
| CCC_01520 | CCC_01521 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.999 |
| CCC_01520 | CCC_01907 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Pyruvate-flavodoxin oxidoreductase. | 0.855 |