STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
gcvPAGlycine dehydrogenase decarboxylating (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (449 aa)    
Predicted Functional Partners:
CCC_03389
Aminomethyltransferase (glycine cleavage system T protein).
 
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.999
CCC_03392
Glycine dehydrogenase decarboxylating (glycine cleavage system P2 protein).
 0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.978
CCC_03903
Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.
 
 
 0.946
CCC_02216
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
 
 
 0.945
CCC_03965
5-aminolevulinate synthase.
 
 
 0.940
CCC_02321
Serine--glyoxylate aminotransferase.
     
 0.922
CCC_00445
Glutamate synthase NADPH large chain.
   
 
 0.907
CCC_02225
Glutamate synthase NADPH large chain.
   
 
 0.907
Your Current Organism:
Magnetospirillum magnetotacticum
NCBI taxonomy Id: 272627
Other names: M. magnetotacticum MS-1, Magnetospirillum magnetotacticum MS-1, Magnetospirillum magnetotacticum str. MS-1, Magnetospirillum magnetotacticum strain MS-1, Magnetospirillum sp. MS-1
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