| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCC_00469 | CCC_02212 | CCC_00469 | CCC_02212 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.746 |
| CCC_00469 | CCC_04093 | CCC_00469 | CCC_04093 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.492 |
| CCC_00469 | bioB | CCC_00469 | CCC_03633 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.458 |
| CCC_00469 | cysC | CCC_00469 | CCC_03591 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sulfate adenylyltransferase subunit 1 / Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.649 |
| CCC_00813 | CCC_01520 | CCC_00813 | CCC_01520 | Branched-chain alpha-keto acid dehydrogenase E1 component beta subunit. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.775 |
| CCC_00813 | CCC_01521 | CCC_00813 | CCC_01521 | Branched-chain alpha-keto acid dehydrogenase E1 component beta subunit. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.775 |
| CCC_00813 | CCC_02212 | CCC_00813 | CCC_02212 | Branched-chain alpha-keto acid dehydrogenase E1 component beta subunit. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.998 |
| CCC_00813 | CCC_04093 | CCC_00813 | CCC_04093 | Branched-chain alpha-keto acid dehydrogenase E1 component beta subunit. | Hypothetical protein. | 0.599 |
| CCC_01520 | CCC_00813 | CCC_01520 | CCC_00813 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Branched-chain alpha-keto acid dehydrogenase E1 component beta subunit. | 0.775 |
| CCC_01520 | CCC_01521 | CCC_01520 | CCC_01521 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.999 |
| CCC_01520 | CCC_02212 | CCC_01520 | CCC_02212 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.987 |
| CCC_01520 | CCC_04093 | CCC_01520 | CCC_04093 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Hypothetical protein. | 0.763 |
| CCC_01520 | cysC | CCC_01520 | CCC_03591 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Sulfate adenylyltransferase subunit 1 / Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.580 |
| CCC_01521 | CCC_00813 | CCC_01521 | CCC_00813 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Branched-chain alpha-keto acid dehydrogenase E1 component beta subunit. | 0.775 |
| CCC_01521 | CCC_01520 | CCC_01521 | CCC_01520 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 3-oxoacyl- acyl-carrier-protein synthase KASII. | 0.999 |
| CCC_01521 | CCC_02212 | CCC_01521 | CCC_02212 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.987 |
| CCC_01521 | CCC_04093 | CCC_01521 | CCC_04093 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Hypothetical protein. | 0.763 |
| CCC_01521 | cysC | CCC_01521 | CCC_03591 | 3-oxoacyl- acyl-carrier-protein synthase KASII. | Sulfate adenylyltransferase subunit 1 / Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.580 |
| CCC_02212 | CCC_00469 | CCC_02212 | CCC_00469 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.746 |
| CCC_02212 | CCC_00813 | CCC_02212 | CCC_00813 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Branched-chain alpha-keto acid dehydrogenase E1 component beta subunit. | 0.998 |