node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38194.1 | ACS38419.1 | MexAM1_META1p0232 | MexAM1_META1p0478 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.935 |
ACS38194.1 | ACS39347.1 | MexAM1_META1p0232 | MexAM1_META1p1485 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.972 |
ACS38194.1 | aroA | MexAM1_META1p0232 | MexAM1_META1p2118 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.415 |
ACS38194.1 | aroB | MexAM1_META1p0232 | MexAM1_META1p1535 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional shikimate kinase (N-terminal) / dehydroquinate synthase (C-terminal) enzyme; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.636 |
ACS38194.1 | aroC | MexAM1_META1p0232 | MexAM1_META1p3197 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.576 |
ACS38194.1 | pabB | MexAM1_META1p0232 | MexAM1_META1p4284 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | 0.406 |
ACS38194.1 | trpE | MexAM1_META1p0232 | MexAM1_META1p5117 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.422 |
ACS38419.1 | ACS38194.1 | MexAM1_META1p0478 | MexAM1_META1p0232 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.935 |
ACS38419.1 | ACS39347.1 | MexAM1_META1p0478 | MexAM1_META1p1485 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.946 |
ACS38419.1 | aroA | MexAM1_META1p0478 | MexAM1_META1p2118 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.872 |
ACS38419.1 | aroB | MexAM1_META1p0478 | MexAM1_META1p1535 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional shikimate kinase (N-terminal) / dehydroquinate synthase (C-terminal) enzyme; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.934 |
ACS38419.1 | aroC | MexAM1_META1p0478 | MexAM1_META1p3197 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.992 |
ACS38419.1 | aroK | MexAM1_META1p0478 | MexAM1_META1p2101 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative shikimate kinase with helix-turn-helix domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.864 |
ACS38419.1 | ffh | MexAM1_META1p0478 | MexAM1_META1p0477 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Signal recognition particle protein, GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual [...] | 0.919 |
ACS38419.1 | pabB | MexAM1_META1p0478 | MexAM1_META1p4284 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Para-aminobenzoate synthase component I (ADC synthase); Function experimentally demonstrated in the studied strain; enzyme. | 0.857 |
ACS38419.1 | trpE | MexAM1_META1p0478 | MexAM1_META1p5117 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.941 |
ACS38419.1 | trpG | MexAM1_META1p0478 | MexAM1_META1p5119 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Aminodeoxychorismate synthase component II, Glutamine amido-transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.928 |
ACS39347.1 | ACS38194.1 | MexAM1_META1p1485 | MexAM1_META1p0232 | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.972 |
ACS39347.1 | ACS38419.1 | MexAM1_META1p1485 | MexAM1_META1p0478 | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.946 |
ACS39347.1 | aroA | MexAM1_META1p1485 | MexAM1_META1p2118 | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.987 |