STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS41137.1Putative adenylate cyclase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (411 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
    
 0.902
pyk-2
Pyruvate kinase; Function of strongly homologous gene; enzyme.
    
 0.902
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
mazG
Nucleoside triphosphate pyrophosphohydrolase MazG; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.900
moaA
Molybdenum biosynthetic protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
  0.805
ACS40849.1
Conserved hypothetical protein with putative cAMP-binding domain; Homologs of previously reported genes of unknown function.
  
 
 0.801
ribAB
3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.801
folE
GTP cyclohydrolase I; Function of strongly homologous gene; enzyme.
     
  0.800
ACS40442.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
   0.768
ACS42509.1
Putative hydrolase of beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.745
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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