STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxCGlutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (85 aa)    
Predicted Functional Partners:
nrd
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.982
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.881
ACS41227.1
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Function of strongly homologous gene; enzyme.
   
 
 0.822
ACS42565.1
Rhodanese domain protein, putative sulfur transferase; Homologs of previously reported genes of unknown function; putative enzyme.
  
  
 0.780
msrA
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.741
msrA-2
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.741
ACS37985.1
Glutaredoxin-like protein; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.698
ACS41333.1
Iron-sulfur cluster assembly accessory protein; Function of strongly homologous gene; factor; Belongs to the HesB/IscA family.
  
  
 0.645
ACS42001.1
Iron-sulfur cluster assembly accessory protein; Function of strongly homologous gene; factor; Belongs to the HesB/IscA family.
  
  
 0.645
ACS37984.1
BolA-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the BolA/IbaG family.
 
 
 0.571
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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