STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS41260.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (290 aa)    
Predicted Functional Partners:
ACS41259.1
Sulfite oxidase, oxidoreductase molybdopterin binding; Function of strongly homologous gene; enzyme.
    0.995
ACS41855.1
Sulfite oxidase, oxidoreductase molybdopterin binding; Function of strongly homologous gene; enzyme.
    0.977
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.478
ACS41261.1
Hypothetical protein; No homology to any previously reported sequences.
       0.466
mauB
Methylamine dehydrogenase large subunit precursor (MADH); Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin; Belongs to the aromatic amine dehydrogenase heavy chain family.
  
     0.433
ACS39088.1
Putative oxidoreductase, molybdopterin binding subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.401
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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