node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML0320 | ML0542 | gene:17574139 | gene:17574363 | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.999 |
ML0320 | ML1014 | gene:17574139 | gene:17574840 | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.999 |
ML0320 | ML1439 | gene:17574139 | gene:17575277 | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. | 0.999 |
ML0320 | rpoA | gene:17574139 | gene:17575809 | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | [alpha] subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
ML0320 | rpoB | gene:17574139 | gene:17575739 | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | [beta] subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
ML0320 | rpoC | gene:17574139 | gene:17575738 | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | [beta]' subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
ML0320 | rpoT | gene:17574139 | gene:17574848 | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.999 |
ML0542 | ML0320 | gene:17574363 | gene:17574139 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | 0.999 |
ML0542 | ML1014 | gene:17574363 | gene:17574840 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.999 |
ML0542 | ML1439 | gene:17574363 | gene:17575277 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. | 0.999 |
ML0542 | ML1624 | gene:17574363 | gene:17575465 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Conserved hypothetical protein; Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis RV2917 SW:YT17_MYCTU (Q10966) (626 aa); Fasta score E(): 0, 79.8% identity in 584 aa overlap and Streptomyces coelicolor TR:Q9S3Y6 (EMBL:AF170560) (597 aa); Fasta score E(): 0, 55.5% identity in 566 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop); To M.tuberculosis Rv2917. | 0.918 |
ML0542 | gmk | gene:17574363 | gene:17574362 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.990 |
ML0542 | mihF | gene:17574363 | gene:17574361 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Putative integration host factor; Similar to M. tuberculosis mihF, Rv1388, possible integration host factor, TR:P71658 (EMBL:AL123456) (190 aa); Fasta score E(): 0, 98.1% identity in 105 aa overlap. Similar to Mycobacterium smegmatis mihF, integration host factor, TR:P96802 (EMBL:U75344) (105 aa); Fasta score E(): 7.5e-32, 94.1% identity in 102 aa overlap. | 0.941 |
ML0542 | rpoA | gene:17574363 | gene:17575809 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | [alpha] subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
ML0542 | rpoB | gene:17574363 | gene:17575739 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | [beta] subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
ML0542 | rpoC | gene:17574363 | gene:17575738 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | [beta]' subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
ML0542 | rpoT | gene:17574363 | gene:17574848 | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.999 |
ML1014 | ML0320 | gene:17574840 | gene:17574139 | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xanthus carD, transcription factor, TR:Q50887 (EMBL:Z56280) (316 aa); Fasta score E(): 9.1e-13, 31.2% identity in 154 aa overlap and to many hypothetical transcription factors. | 0.999 |
ML1014 | ML0542 | gene:17574840 | gene:17574363 | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.999 |
ML1014 | ML1439 | gene:17574840 | gene:17575277 | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. | 0.999 |