Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ML0628 | ML0630 | gene:17574449 | gene:17574451 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | Similar to M. tuberculosis Rv2365c, hypothetical protein, TR:O05833 (EMBL:AL123456) (113 aa); Fasta score E(): 1.5e-22, 67.9% identity in 106 aa overlap. Similar to Streptomyces coelicolor SCC77.05, hypothetical protein, TR:Q9RDF3 (EMBL:AL136503) (132 aa); Fasta score E(): 3.3e-06, 39.4% identity in 99 aa overlap. Previously sequenced as TR:Q49767 (EMBL:U00016) (108 aa); Fasta score E(): 0, 100.0% identity in 108 aa overlap. | 0.784 |
| ML0628 | dnaJ2 | gene:17574449 | gene:17574446 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.752 |
| ML0628 | era | gene:17574449 | gene:17574452 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | Putative Era-family GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.822 |
| ML0628 | gcvB | gene:17574449 | gene:17575924 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | Glycine decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.750 |
| ML0628 | gpsI | gene:17574449 | gene:17574680 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | Putative polyribonucleotide phosphorylase / guanosine pentaphosphate synthetase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.740 |
| ML0628 | phoH | gene:17574449 | gene:17574448 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | phoH-family protein; Similar to M. tuberculosis phoH, Rv2372c, phoH-family protein, SW:PHOL_MYCTU (O05830) (352 aa); Fasta score E(): 0, 88.9% identity in 352 aa overlap. Similar to many hypothetical proteins and to Escherichia coli phoH, phosphate starvation-inducible protein, SW:PHOH_ECOLI (P31544) (354 aa); Fasta score E(): 1.2e-29, 36.8% identity in 304 aa overlap. Previously sequenced as SW:PHOL_MYCLE (Q49751) (349 aa); Fasta score E(): 0, 99.7% identity in 349 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML1951, except and N- and C-termini. | 0.961 |
| ML0628 | rplQ | gene:17574449 | gene:17575808 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | Similar to M. tuberculosis 50S ribosomal protein L17 rplQ Rv3456c SW:RL17_MYCTU (O06323) (180 aa); Fasta score E(): 0, 81.9% identity in 171 aa overlap. Contains Pfam match to entry PF01196 Ribosomal_L17, Ribosomal protein L17. | 0.766 |
| ML0628 | rplX | gene:17574449 | gene:17575696 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.734 |
| ML0628 | rpsQ | gene:17574449 | gene:17575702 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.730 |
| ML0628 | sodA | gene:17574449 | gene:17573884 | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.879 |
| ML0630 | ML0628 | gene:17574451 | gene:17574449 | Similar to M. tuberculosis Rv2365c, hypothetical protein, TR:O05833 (EMBL:AL123456) (113 aa); Fasta score E(): 1.5e-22, 67.9% identity in 106 aa overlap. Similar to Streptomyces coelicolor SCC77.05, hypothetical protein, TR:Q9RDF3 (EMBL:AL136503) (132 aa); Fasta score E(): 3.3e-06, 39.4% identity in 99 aa overlap. Previously sequenced as TR:Q49767 (EMBL:U00016) (108 aa); Fasta score E(): 0, 100.0% identity in 108 aa overlap. | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.784 |
| ML0630 | dnaJ2 | gene:17574451 | gene:17574446 | Similar to M. tuberculosis Rv2365c, hypothetical protein, TR:O05833 (EMBL:AL123456) (113 aa); Fasta score E(): 1.5e-22, 67.9% identity in 106 aa overlap. Similar to Streptomyces coelicolor SCC77.05, hypothetical protein, TR:Q9RDF3 (EMBL:AL136503) (132 aa); Fasta score E(): 3.3e-06, 39.4% identity in 99 aa overlap. Previously sequenced as TR:Q49767 (EMBL:U00016) (108 aa); Fasta score E(): 0, 100.0% identity in 108 aa overlap. | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.486 |
| ML0630 | era | gene:17574451 | gene:17574452 | Similar to M. tuberculosis Rv2365c, hypothetical protein, TR:O05833 (EMBL:AL123456) (113 aa); Fasta score E(): 1.5e-22, 67.9% identity in 106 aa overlap. Similar to Streptomyces coelicolor SCC77.05, hypothetical protein, TR:Q9RDF3 (EMBL:AL136503) (132 aa); Fasta score E(): 3.3e-06, 39.4% identity in 99 aa overlap. Previously sequenced as TR:Q49767 (EMBL:U00016) (108 aa); Fasta score E(): 0, 100.0% identity in 108 aa overlap. | Putative Era-family GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.897 |
| ML0630 | phoH | gene:17574451 | gene:17574448 | Similar to M. tuberculosis Rv2365c, hypothetical protein, TR:O05833 (EMBL:AL123456) (113 aa); Fasta score E(): 1.5e-22, 67.9% identity in 106 aa overlap. Similar to Streptomyces coelicolor SCC77.05, hypothetical protein, TR:Q9RDF3 (EMBL:AL136503) (132 aa); Fasta score E(): 3.3e-06, 39.4% identity in 99 aa overlap. Previously sequenced as TR:Q49767 (EMBL:U00016) (108 aa); Fasta score E(): 0, 100.0% identity in 108 aa overlap. | phoH-family protein; Similar to M. tuberculosis phoH, Rv2372c, phoH-family protein, SW:PHOL_MYCTU (O05830) (352 aa); Fasta score E(): 0, 88.9% identity in 352 aa overlap. Similar to many hypothetical proteins and to Escherichia coli phoH, phosphate starvation-inducible protein, SW:PHOH_ECOLI (P31544) (354 aa); Fasta score E(): 1.2e-29, 36.8% identity in 304 aa overlap. Previously sequenced as SW:PHOL_MYCLE (Q49751) (349 aa); Fasta score E(): 0, 99.7% identity in 349 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML1951, except and N- and C-termini. | 0.647 |
| dnaJ2 | ML0628 | gene:17574446 | gene:17574449 | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.752 |
| dnaJ2 | ML0630 | gene:17574446 | gene:17574451 | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Similar to M. tuberculosis Rv2365c, hypothetical protein, TR:O05833 (EMBL:AL123456) (113 aa); Fasta score E(): 1.5e-22, 67.9% identity in 106 aa overlap. Similar to Streptomyces coelicolor SCC77.05, hypothetical protein, TR:Q9RDF3 (EMBL:AL136503) (132 aa); Fasta score E(): 3.3e-06, 39.4% identity in 99 aa overlap. Previously sequenced as TR:Q49767 (EMBL:U00016) (108 aa); Fasta score E(): 0, 100.0% identity in 108 aa overlap. | 0.486 |
| dnaJ2 | phoH | gene:17574446 | gene:17574448 | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | phoH-family protein; Similar to M. tuberculosis phoH, Rv2372c, phoH-family protein, SW:PHOL_MYCTU (O05830) (352 aa); Fasta score E(): 0, 88.9% identity in 352 aa overlap. Similar to many hypothetical proteins and to Escherichia coli phoH, phosphate starvation-inducible protein, SW:PHOH_ECOLI (P31544) (354 aa); Fasta score E(): 1.2e-29, 36.8% identity in 304 aa overlap. Previously sequenced as SW:PHOL_MYCLE (Q49751) (349 aa); Fasta score E(): 0, 99.7% identity in 349 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop); Similar to ML1951, except and N- and C-termini. | 0.447 |
| dnaJ2 | rplQ | gene:17574446 | gene:17575808 | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Similar to M. tuberculosis 50S ribosomal protein L17 rplQ Rv3456c SW:RL17_MYCTU (O06323) (180 aa); Fasta score E(): 0, 81.9% identity in 171 aa overlap. Contains Pfam match to entry PF01196 Ribosomal_L17, Ribosomal protein L17. | 0.735 |
| dnaJ2 | rplX | gene:17574446 | gene:17575696 | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.608 |
| dnaJ2 | rpsQ | gene:17574446 | gene:17575702 | DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.667 |
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