node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ML0916 | ddlA | gene:17574742 | gene:17575521 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | D-alanine-D-alanine ligase A; Cell wall formation. | 0.707 |
ML0916 | ftsW | gene:17574742 | gene:17574739 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | Putative cell division protein FtsW; Identical to the previously sequenced Mycobacterium leprae cell division protein, FtsW, TR:O69553 (EMBL:AL022602) (534 aa); Fasta score E(): 0, 99.8% identity in 534 aa overlap(EMBL:AL022602). Also highly similar many other FtsW-family proteins involved in cell wall formation e.g. from Mycobacterium tuberculosis FtsW-like protein SW:FTWH_MYCTU (SW:O06223) (524 aa); Fasta score E(): 0, 76.5% identity in 528 aa overlap(SW:O06223) and Escherichia coli FtsW SW:FTSW_ECOLI (SW:P16457) (414 aa); Fasta score E(): 3.6e-31, 37.0% identity in 370 aa overlap(SW [...] | 0.994 |
ML0916 | mraY | gene:17574742 | gene:17574737 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | phospho-N-acetylmuramoyl- pentapeptidetransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.917 |
ML0916 | murB | gene:17574742 | gene:17576310 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.549 |
ML0916 | murC | gene:17574742 | gene:17574741 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | UDP-N-acetyl-muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.977 |
ML0916 | murD | gene:17574742 | gene:17574738 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.975 |
ML0916 | murE | gene:17574742 | gene:17574735 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.924 |
ML0916 | murF | gene:17574742 | gene:17574736 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.959 |
ML0916 | murG | gene:17574742 | gene:17574740 | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.989 |
ddlA | ML0916 | gene:17575521 | gene:17574742 | D-alanine-D-alanine ligase A; Cell wall formation. | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.707 |
ddlA | ftsW | gene:17575521 | gene:17574739 | D-alanine-D-alanine ligase A; Cell wall formation. | Putative cell division protein FtsW; Identical to the previously sequenced Mycobacterium leprae cell division protein, FtsW, TR:O69553 (EMBL:AL022602) (534 aa); Fasta score E(): 0, 99.8% identity in 534 aa overlap(EMBL:AL022602). Also highly similar many other FtsW-family proteins involved in cell wall formation e.g. from Mycobacterium tuberculosis FtsW-like protein SW:FTWH_MYCTU (SW:O06223) (524 aa); Fasta score E(): 0, 76.5% identity in 528 aa overlap(SW:O06223) and Escherichia coli FtsW SW:FTSW_ECOLI (SW:P16457) (414 aa); Fasta score E(): 3.6e-31, 37.0% identity in 370 aa overlap(SW [...] | 0.735 |
ddlA | mraY | gene:17575521 | gene:17574737 | D-alanine-D-alanine ligase A; Cell wall formation. | phospho-N-acetylmuramoyl- pentapeptidetransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.690 |
ddlA | murA | gene:17575521 | gene:17574977 | D-alanine-D-alanine ligase A; Cell wall formation. | UDP-N-acetylglucosamine-1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.819 |
ddlA | murB | gene:17575521 | gene:17576310 | D-alanine-D-alanine ligase A; Cell wall formation. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.862 |
ddlA | murC | gene:17575521 | gene:17574741 | D-alanine-D-alanine ligase A; Cell wall formation. | UDP-N-acetyl-muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.987 |
ddlA | murD | gene:17575521 | gene:17574738 | D-alanine-D-alanine ligase A; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.882 |
ddlA | murE | gene:17575521 | gene:17574735 | D-alanine-D-alanine ligase A; Cell wall formation. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.915 |
ddlA | murF | gene:17575521 | gene:17574736 | D-alanine-D-alanine ligase A; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ddlA | murG | gene:17575521 | gene:17574740 | D-alanine-D-alanine ligase A; Cell wall formation. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.926 |
ftsW | ML0916 | gene:17574739 | gene:17574742 | Putative cell division protein FtsW; Identical to the previously sequenced Mycobacterium leprae cell division protein, FtsW, TR:O69553 (EMBL:AL022602) (534 aa); Fasta score E(): 0, 99.8% identity in 534 aa overlap(EMBL:AL022602). Also highly similar many other FtsW-family proteins involved in cell wall formation e.g. from Mycobacterium tuberculosis FtsW-like protein SW:FTWH_MYCTU (SW:O06223) (524 aa); Fasta score E(): 0, 76.5% identity in 528 aa overlap(SW:O06223) and Escherichia coli FtsW SW:FTSW_ECOLI (SW:P16457) (414 aa); Fasta score E(): 3.6e-31, 37.0% identity in 370 aa overlap(SW [...] | Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.994 |