STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ML1006Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (161 aa)    
Predicted Functional Partners:
ML1005
Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.691
ksgA
Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.527
ML1004
Possible conserved membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49846 (EMBL:U00019) (164 aa); Fasta score E(): 0, 100.0% identity in 164 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2719c TR:O07218 (EMBL:Z96072) (165 aa); Fasta score E(): 1.8e-23, 55.2% identity in 163 aa overlap. Contains a possible membrane spanning hydrophobic domain.
     
 0.504
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: M. leprae TN, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN
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