Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis RV1693 TR:O33195 (EMBL:Z98268) (58 aa); Fasta score E(): 9.7e-13, 73.8% identity in 61 aa overlap.

RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity).

Cytotoxin/hemolysin; Highly similar to several proposed hemolysins including: Mycobacterium ulcerans TlyA TR:CAB83047 (EMBL:AJ271681) (281 aa); Fasta score E(): 0, 81.0% identity in 268 aa overlap, Treponema hyodysenteriae hemolysin A SW:HLYA_TREHY (Q06803) (240 aa); Fasta score E(): 2.3e-23, 34.9% identity in 238 aa overlap and Mycobacterium tuberculosis TR:Q50760 (EMBL:X98295) (268 aa); Fasta score E(): 0, 78.4% identity in 268 aa overlap. Contains possible membrane spanning hydrophobic domains.

Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]

Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.

Conserved hypothetical protein; Involved in DNA repair and RecF pathway recombination.

Holliday junction DNA helicase component; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

Possible conserved secreted protein; Pore-forming protein, which is involved in efflux of copper across the outer membrane. Essential for copper resistance and maintenance of a low intracellular copper concentration (By similarity); Belongs to the MctB (TC 1.B.50) family.