Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ML1465 | proA | gene:17575303 | gene:17575296 | GTP1/Obg-family GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | [gamma]-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.425 |
| ML1465 | proB | gene:17575303 | gene:17575302 | GTP1/Obg-family GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.943 |
| ML1465 | rplU | gene:17575303 | gene:17575305 | GTP1/Obg-family GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.927 |
| ML1465 | rpmA | gene:17575303 | gene:17575304 | GTP1/Obg-family GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Highly similar to many 50s ribosomal proteins (L27) including: Escherichia coli SW:RL27_ECOLI (P02427) (84 aa); Fasta score E(): 5.8e-16, 63.9% identity in 83 aa overlap and Mycobacterium tuberculosis RV2441C SW:RL27_MYCTU (Z8145) (86 aa); Fasta score E(): 3.3e-28, 93.8% identity in 81 aa overlap. Contains Pfam match to entry PF01016 Ribosomal_L27, Ribosomal L27 protein. Contains PS00831 Ribosomal protein L27 signature; Belongs to the bacterial ribosomal protein bL27 family. | 0.963 |
| ML1468 | proB | gene:17575306 | gene:17575302 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.633 |
| ML1468 | rplU | gene:17575306 | gene:17575305 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.707 |
| ML1468 | rpmA | gene:17575306 | gene:17575304 | Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis RV2444C TR:P71905 (EMBL:Z81451) (953 aa); Fasta score E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain. | Highly similar to many 50s ribosomal proteins (L27) including: Escherichia coli SW:RL27_ECOLI (P02427) (84 aa); Fasta score E(): 5.8e-16, 63.9% identity in 83 aa overlap and Mycobacterium tuberculosis RV2441C SW:RL27_MYCTU (Z8145) (86 aa); Fasta score E(): 3.3e-28, 93.8% identity in 81 aa overlap. Contains Pfam match to entry PF01016 Ribosomal_L27, Ribosomal L27 protein. Contains PS00831 Ribosomal protein L27 signature; Belongs to the bacterial ribosomal protein bL27 family. | 0.692 |
| argB | argR | gene:17575247 | gene:17575250 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.994 |
| argB | gltB | gene:17575247 | gene:17573873 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | 0.838 |
| argB | proA | gene:17575247 | gene:17575296 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | [gamma]-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.869 |
| argB | proB | gene:17575247 | gene:17575302 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.881 |
| argR | argB | gene:17575250 | gene:17575247 | Arginine repressor; Regulates arginine biosynthesis genes. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.994 |
| argR | gltB | gene:17575250 | gene:17573873 | Arginine repressor; Regulates arginine biosynthesis genes. | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | 0.505 |
| argR | proB | gene:17575250 | gene:17575302 | Arginine repressor; Regulates arginine biosynthesis genes. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.591 |
| gltB | argB | gene:17573873 | gene:17575247 | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.838 |
| gltB | argR | gene:17573873 | gene:17575250 | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.505 |
| gltB | proA | gene:17573873 | gene:17575296 | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | [gamma]-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.907 |
| gltB | proB | gene:17573873 | gene:17575302 | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.767 |
| gltB | proC | gene:17573873 | gene:17576293 | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.637 |
| gltB | ribA | gene:17573873 | gene:17574380 | Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocystis sp. gltB, ferredoxin-dependent glutamate synthase 1, SW:GLTB_SYNY3 (P55037) (1550 aa); Fasta score E(): 0, 57.2% identity in 1525 aa overlap. Contains Pfam match to entry PF01493 DUF14, Domain of unknown function. Contains Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase. Contains PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. | Putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.493 |
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