STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phoS2PstS component of phosphate uptake; Part of the ABC transporter complex PstSACB involved in phosphate import. (369 aa)    
Predicted Functional Partners:
pstA1
Membrane-bound component of phosphate transport; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
 0.998
pstC2
Membrane-bound component of phosphate transport; Part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
 0.998
phoT
Phosphate transport system ABC transporter; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 
 0.981
phoS3
Phosphate-binding protein 3 precursor; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
  
  
 
0.908
phoY1
Phosphate transport system regulator; Plays a role in the regulation of phosphate uptake.
 
  
 0.647
glnH
Similar to M. tuberculosis glnH, Rv0411c, putative glutamine-binding protein, TR:P96257 (EMBL:AL123456) (328 aa); Fasta score E(): 0, 79.3% identity in 328 aa overlap. Similar to many bacterial solute-binding proteins e.g. Bacillus stearothermophilus glnH, glutamine-binding protein, SW:GLNH_BACST (P27676) (262 aa); Fasta score E(): 3.7e-23, 38.1% identity in 194 aa overlap. Previously sequenced as TR:Q9ZBL7 (EMBL:AL035159) (325 aa); Fasta score E(): 0, 100.0% identity in 325 aa overlap. Contains a probable N-terminal signal sequence. Contains Pfam match to entry PF00497 SBP_bac_3, Bact [...]
  
  
 0.597
ML2440
Probable two-component system sensor histidine kinase; Probably forms part of a two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 (Probable).
  
  
 0.534
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: M. leprae TN, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN
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