STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ML2433Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical 33.1 kda protein Rv0497 SW:Y497_MYCTU (Q11162) (310 aa) fasta scores: E(): 4.6e-21, 54.2% id in 356 aa. Contains multiple possible membrane spanning hydrophobic domains. (355 aa)    
Predicted Functional Partners:
ML2434
Conserved hypothetical protein; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain.
       0.859
ML2432
Similar to Mycobacterium tuberculosis hypothetical protein Rv0498 SW:Y498_MYCTU (Q11163) (280 aa) fasta scores: E(): 0, 89.3% id in 280 aa, and to Streptomyces coelicolor hypothetical protein TR:Q9X8H0 (EMBL:AL049819) (285 aa) fasta scores: E(): 3.2e-30, 51.6% id in 273 aa.
       0.812
ML1539
Probable membrane protein; Similar to several Mycobacterium tuberculosis proteins of undefined function e.g. putative membrane protein RV1795 TR:O53944 (EMBL:AL022021) (503 aa); Fasta score E(): 0, 76.9% identity in 503 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.
  
     0.765
ML2596
Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0176 TR:O07420 (EMBL:Z97050) fasta scores: E(): 0, 54.9% id in 319 aa. Contains multiple possible membrane spanning hydrophobic domains.
  
    0.762
ML1544
Conserved membrane protein; Highly similar to many Mycobacterium tuberculosis proteins of unknown function including:RV1782 TR:O53933 (EMBL:AL022021) (506 aa); Fasta score E(): 0, 82.6% identity in 506 aa overlap. Contains a possible membrane spanning hydrophobic domain; Similar to ML0054.
  
     0.759
ML0185
Putative membrane protein; Similar to M.tuberculosis Rv0996, hypothetical protein, TR:O05579 (EMBL:AL123456) (358 aa); Fasta score E(): 0, 66.4% identity in 360 aa overlap. Previously sequenced as TR:Q9Z5F8 (EMBL:AL035500) (342 aa); Fasta score E(): 0, 100.0% identity in 342 aa overlap. Contains hydrophobic, possible membrane-spanning regions.
  
     0.758
ML1270
Possible conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1610 TR:O06128 (EMBL:Z95554) (235 aa); Fasta score E(): 0, 65.8% identity in 231 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00218 IGPS, Indole-3-glycerol phosphate synthases.
  
     0.748
ML0810
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 42.5 kDa protein Rv3212 or MTCY07D11.14c (407 aa) TR:O05854 (EMBL:Z95120) fasta scores: E(): 0, 79.9% id in 407 aa. Contains hydrophobic, possible membrane-spanning region.
  
     0.746
ML2435
Similar to Mycobacterium tuberculosis hypothetical protein Rv0495c SW:Y495_MYCTU (Q11160) (296 aa) fasta scores: E(): 0, 82.7% id in 271 aa, and to Streptomyces coelicolor hypothetical protein TR:Q9X8H2 (EMBL:AL049819) (271 aa) fasta scores: E(): 0, 48.4% id in 250 aa.
       0.745
ML0073
Putative membrane protein; Similar to M. tuberculosis Rv3843c, putative membrane protein, TR:P96235 (EMBL:Z83864) (342 aa); Fasta score E(): 0, 63.0% identity in 349 aa overlap. Contains hydrophobic, possible membrane-spanning regions.
  
     0.744
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: M. leprae TN, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.