STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ML0029Possible membrane protein; Contains a region similar to part of several bacterial hypothetical membrane proteins e.g. Streptomyces coelicolor SC4B5.06, putative transmembrane protein, TR:Q9ZBW2 (EMBL:AL034443) (345 aa); Fasta score E(): 2.4e-14, 54.1% identity in 109 aa overlap. The coding frame predicted by GC frameplot changes to either side of this region of similarity, suggesting that an ancestral CDS was disrupted. Given this, ML0029 may not be functional. Contains hydrophobic, possible membrane-spanning regions. (201 aa)    
Predicted Functional Partners:
ML0030
Putative membrane protein; Similar to M. tuberculosis Rv0039c, hypothetical protein, TR:P71696 (EMBL:AL123456) (115 aa); Fasta score E(): 2.2e-25, 63.2% identity in 114 aa overlap. Previously sequenced as TR:O32871 (EMBL:Z70722) (113 aa); Fasta score E(): 0, 100.0% identity in 113 aa overlap. Contains hydrophobic, possible membrane-spanning regions.
       0.724
arsC
Putative arsenate reductase; Similar to many e.g. Escherichia coli arsC, arsenate reductase, SW:ARC1_ECOLI (P08692) (141 aa); Fasta score E(): 1.7e-07, 38.8% identity in 103 aa overlap. Similar to proteins which expand the substrate specificity of arsAB pump.
  
     0.473
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: M. leprae TN, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN
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