STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPE9450Phosphoribosylpyrophosphate synthetase. (332 aa)    
Predicted Functional Partners:
MYPE5090
Pyruvate dehydrogenase E1 component subunit beta.
  
 0.988
MYPE770
Transketolase; Belongs to the transketolase family.
   
 
 0.946
MYPE4510
Transketolase I; Belongs to the transketolase family.
   
 
 0.946
MYPE680
Ribose 5-phosphate and galactose-6-phosphate isomerase.
    
 0.941
MYPE5100
Dihydrolipoamide acetyltransferase of pyruvate dehydrogenase E2 component.
  
 0.938
MYPE5110
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase E3 component.
  
 0.925
MYPE7840
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.845
MYPE9440
Predicted nucleotidyltransferase; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
       0.816
MYPE3150
Inosine-5'-monophosphate dehydrogenase.
  
 
 0.735
MYPE5080
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 0.722
Your Current Organism:
Mycoplasma penetrans
NCBI taxonomy Id: 272633
Other names: M. penetrans HF-2, Mycoplasma penetrans HF-2, Mycoplasma penetrans str. HF-2, Mycoplasma penetrans strain HF-2
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