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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (206 aa)    
Predicted Functional Partners:
udk
Uridine kinase; MPN561(new), 281(Himmelreich et al., 1996).
 
 0.996
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.961
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
   
 0.959
lacA
Galactose-6-phosphate isomerase/ribose 5-phosphate isomerase B; Catalyzes the interconversion of ribulose-5-P and ribose-5-P. Belongs to the LacAB/RpiB family.
 
    0.924
B01_orf108
Hydrolase; MPN032(new), 122(Himmelreich et al., 1996).
       0.773
tdk
Thymidine kinase; MPN044(new), 110(Himmelreich et al., 1996).
     
 0.748
polC
DNA polymerase III (dnaE) alpha chain; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity; Belongs to the DNA polymerase type-C family. PolC subfamily.
  
   0.682
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
 0.608
hpt
Hypoxanthine-guanine phosphoribosyltransferase; MPN672(new), 170(Himmelreich et al., 1996).
  
  
 0.586
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.585
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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