node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D09_orf127a | nusG | MPN_070 | MPN_067 | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | 0.741 |
D09_orf127a | prs | MPN_070 | MPN_073 | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.775 |
D09_orf127a | rpmG2 | MPN_070 | MPN_069 | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | Ribosomal protein L33 type2; MPN069(new); Belongs to the bacterial ribosomal protein bL33 family. | 0.741 |
D09_orf127a | secE | MPN_070 | MPN_068 | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | SecE; MPN068(new), 086(Himmelreich et al., 1996). | 0.741 |
D09_orf127a | smpB | MPN_070 | MPN_074 | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | Hypothetical protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.773 |
D09_orf127a | yabC | MPN_070 | MPN_071 | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.779 |
D09_orf127a | yabF | MPN_070 | MPN_072 | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | Nucelotidyl transferase/polynicleotide cleavage-like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step; Belongs to the ribonuclease M5 family. | 0.773 |
ksgA | nusG | MPN_679 | MPN_067 | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | 0.421 |
ksgA | prs | MPN_679 | MPN_073 | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.488 |
ksgA | rnc | MPN_679 | MPN_545 | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.416 |
ksgA | smpB | MPN_679 | MPN_074 | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Hypothetical protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.491 |
ksgA | yabC | MPN_679 | MPN_071 | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.818 |
ksgA | yabF | MPN_679 | MPN_072 | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Nucelotidyl transferase/polynicleotide cleavage-like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step; Belongs to the ribonuclease M5 family. | 0.828 |
ksgA | ybeY | MPN_679 | MPN_569 | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Predicted metalloenzyme interacting with hemolysin; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.419 |
nusG | D09_orf127a | MPN_067 | MPN_070 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | Unknown; MPN070(new), 085(Himmelreich et al., 1996). | 0.741 |
nusG | ksgA | MPN_067 | MPN_679 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.421 |
nusG | prs | MPN_067 | MPN_073 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.852 |
nusG | rpmG2 | MPN_067 | MPN_069 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | Ribosomal protein L33 type2; MPN069(new); Belongs to the bacterial ribosomal protein bL33 family. | 0.932 |
nusG | secE | MPN_067 | MPN_068 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | SecE; MPN068(new), 086(Himmelreich et al., 1996). | 0.977 |
nusG | smpB | MPN_067 | MPN_074 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | Hypothetical protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.783 |