STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Orf6Cytadherence protein; MPN142(new), 013(Himmelreich et al., 1996). (1218 aa)    
Predicted Functional Partners:
P1
Adhesin P1; The protein is the major adhesin mediating the attachment of this mycoplasma to respiratory epithelium.
  
 
0.996
nrnA
DHH family phosphoesterases; Bifunctional enzyme which has both oligoribonuclease and pAp- phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for longer oligomers. Also degrades 11- and 24-mers, but less efficiently. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction , and 11-mers in a 5' to 3' direction. Converts 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP; Belongs to the NrnA oligoribonuclease family.
     
 0.949
E07_orf175
Hypothetical protein; MPN143(new), 012(Himmelreich et al., 1996).
  
  
 0.808
hmw1
Cytadherence accessory protein HMW1; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity).
   
  
 0.693
p30
30K adhesin-related protein; Adhesin necessary for successful cytadherence and virulence.
   
  
 0.640
E07_orf166
Hypothetical protein; MPN138(new), 017(Himmelreich et al., 1996); see: MPN013; Belongs to the UPF0134 family.
  
  
 0.638
Orf7
Conserved hypothetical protein; MPN450(new), 390(Himmelreich et al., 1996).
      
 0.633
F11_orf346
Conserved hypothetical protein; MPN404(new), 435(Himmelreich et al., 1996).
   
  
 0.618
P65
Conserved hypothetical protein; MPN309(new), 528(Himmelreich et al., 1996).
   
  
 0.611
E07_orf228
Hypothetical protein; MPN137(new), 018(Himmelreich et al., 1996); see: MPN013; Belongs to the UPF0134 family.
  
  
 0.602
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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