close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacBConserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacB/CdaS subfamily. (202 aa)    
Predicted Functional Partners:
vacB
3'-5' exoribonuclease, RNase R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
    0.808
G12_orf325
Phosphodiesterase; MPN549(new), 293(Himmelreich et al., 1996); Belongs to the mgp1/MG371 family.
     
 0.808
cpsG
CpsG; MPN066(new), 088(Himmelreich et al., 1996); similar to phosphomannomutase and phosphoglucomutase; Belongs to the phosphohexose mutase family.
   
 
 0.769
secG
SecG; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family.
       0.766
gatA
Glu-tRNA amidotransferase, subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln) (By similarity).
  
   0.750
trxB
Thioredoxin reductase; MPN240(new), 592(Himmelreich et al., 1996).
  
    0.732
pet112
Glu-tRNA(Gln) amidotransferase, subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity); Belongs to the GatB/GatE family. GatB subfamily.
  
    0.701
G07_orf479
Glu-tRNA amidotransferase subunit C; MPN236(new), 596(Himmelreich et al., 1996); contains unknown TM contacting N terminal domain.
  
    0.693
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
    0.682
K04_orf222
Conserved hypothetical protein; MPN239(new), 593(Himmelreich et al., 1996).
       0.655
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
Server load: low (24%) [HD]