STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A65_orf251bConserved hypothetical protein; MPN255(new), 579(Himmelreich et al., 1996). (251 aa)    
Predicted Functional Partners:
K05_orf169
Conserved hypothetical protein; MPN673(new), 169(Himmelreich et al., 1996).
  
  
 0.868
galE
UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
  
    0.783
A65_orf223
Conserved hypothetical protein; MPN256(new), 578(Himmelreich et al., 1996).
  
    0.780
yjcW
Sugar (ribose/galactose) ABC transporter ATP-binding subunit; Part of the ABC transporter complex involved in carbohydrates import. Probably responsible for energy coupling to the transport system (By similarity).
  
    0.755
MPN_254
Conserved hypothetical protein; MPN254(new); Belongs to the CinA family.
  
    0.745
A65_orf517
Sugar (ribose/galactose) ABC transporter permease subunit, but probably C-terminal; MPN259(new), 575(Himmelreich et al., 1996).
  
    0.703
rbsC
Sugar (ribose/galactose) ABC transporter permease subunit; MPN260(new), 574(Himmelreich et al., 1996).
  
    0.703
pgsA
Phosphatidylglycerophosphate synthase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.701
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.691
cfxE
D-ribulose-5-phosphate 3 epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
  
    0.674
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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