Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
hsdRType I restriction enzyme-like protein; Subunit R is required for both nuclease and ATPase activities, but not for modification. (206 aa)    
Predicted Functional Partners:
hsdR-2
Type I restriction enzyme-like protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
   
 0.985
hsdM
Type I restriction enzyme HsdM; Methylation of specific adenine residues; required for both restriction and modification activities.
 
  
 0.972
H91_orf115
Type I restriction enzyme-like protein; HsdR; MPN346(new), 491(Himmelreich et al., 1996).
     
 0.704
hsdS
Hypothetical protein; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).
  
  
 0.546
hsdS-2
Hypothetical protein; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).
  
  
 0.539
C09_orf718
Conserved hypothetical protein; MPN110(new), 045(Himmelreich et al., 1996).
  
  
 0.536
P02_orf363V
Type I restriction enzyme ecokI specificity protein; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).
  
  
 0.492
E30_orf375
Specificity determining subunit for restriction enzyme belonging to the K family of S proteins; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).
  
  
 0.483
hsdS1B
HsdS1B; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).
  
  
 0.477
H91_orf330
Hypothetical protein; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).
  
  
 0.465
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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