node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A19_orf591 | E07_orf301 | MPN_372 | MPN_133 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | Putative lipoprotein; MPN133(new), 022(Himmelreich et al., 1996). | 0.715 |
A19_orf591 | MPN_371 | MPN_372 | MPN_371 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | Hypothetical protein; MPN371(new), 466(Himmelreich et al., 1996). | 0.744 |
A19_orf591 | MPN_388 | MPN_372 | MPN_388 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | Conserved hypothetical protein; MPN388(new). | 0.564 |
A19_orf591 | Orf6 | MPN_372 | MPN_142 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | Cytadherence protein; MPN142(new), 013(Himmelreich et al., 1996). | 0.512 |
A19_orf591 | P02_orf140 | MPN_372 | MPN_488 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | NifU-like; MPN488(new), 353(Himmelreich et al., 1996); complementing transferase subunit for MPN488. | 0.945 |
A19_orf591 | P1 | MPN_372 | MPN_141 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | Adhesin P1; The protein is the major adhesin mediating the attachment of this mycoplasma to respiratory epithelium. | 0.620 |
A19_orf591 | cpsG | MPN_372 | MPN_066 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | CpsG; MPN066(new), 088(Himmelreich et al., 1996); similar to phosphomannomutase and phosphoglucomutase; Belongs to the phosphohexose mutase family. | 0.542 |
A19_orf591 | hmw1 | MPN_372 | MPN_447 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | Cytadherence accessory protein HMW1; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity). | 0.528 |
A19_orf591 | hmw3 | MPN_372 | MPN_452 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | Cytadherence accessory protein HMW3; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism. | 0.536 |
A19_orf591 | p30 | MPN_372 | MPN_453 | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | 30K adhesin-related protein; Adhesin necessary for successful cytadherence and virulence. | 0.623 |
E07_orf301 | A19_orf591 | MPN_133 | MPN_372 | Putative lipoprotein; MPN133(new), 022(Himmelreich et al., 1996). | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | 0.715 |
MPN_371 | A19_orf591 | MPN_371 | MPN_372 | Hypothetical protein; MPN371(new), 466(Himmelreich et al., 1996). | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | 0.744 |
MPN_388 | A19_orf591 | MPN_388 | MPN_372 | Conserved hypothetical protein; MPN388(new). | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | 0.564 |
Orf6 | A19_orf591 | MPN_142 | MPN_372 | Cytadherence protein; MPN142(new), 013(Himmelreich et al., 1996). | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | 0.512 |
Orf6 | P1 | MPN_142 | MPN_141 | Cytadherence protein; MPN142(new), 013(Himmelreich et al., 1996). | Adhesin P1; The protein is the major adhesin mediating the attachment of this mycoplasma to respiratory epithelium. | 0.996 |
Orf6 | hmw1 | MPN_142 | MPN_447 | Cytadherence protein; MPN142(new), 013(Himmelreich et al., 1996). | Cytadherence accessory protein HMW1; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity). | 0.693 |
Orf6 | hmw3 | MPN_142 | MPN_452 | Cytadherence protein; MPN142(new), 013(Himmelreich et al., 1996). | Cytadherence accessory protein HMW3; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism. | 0.403 |
Orf6 | p30 | MPN_142 | MPN_453 | Cytadherence protein; MPN142(new), 013(Himmelreich et al., 1996). | 30K adhesin-related protein; Adhesin necessary for successful cytadherence and virulence. | 0.640 |
P02_orf140 | A19_orf591 | MPN_488 | MPN_372 | NifU-like; MPN488(new), 353(Himmelreich et al., 1996); complementing transferase subunit for MPN488. | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | 0.945 |
P1 | A19_orf591 | MPN_141 | MPN_372 | Adhesin P1; The protein is the major adhesin mediating the attachment of this mycoplasma to respiratory epithelium. | Pertussis toxin subunit s1-like protein; Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells; Belongs to the bacterial exotoxin subunit A family. | 0.620 |