STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Orf8Conserved hypothetical protein; MPN449(new), 391(Himmelreich et al., 1996). (448 aa)    
Predicted Functional Partners:
Orf7
Conserved hypothetical protein; MPN450(new), 390(Himmelreich et al., 1996).
     
 0.850
come3
Competence locus operon protein 3-like protein; MPN451(new), 389(Himmelreich et al., 1996); similar to Swiss-Prot Accession Number P39695.
       0.770
hmw3
Cytadherence accessory protein HMW3; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism.
       0.639
p30
30K adhesin-related protein; Adhesin necessary for successful cytadherence and virulence.
  
    0.631
H08_orf263
Conserved hypothetical protein; MPN448(new), 392(Himmelreich et al., 1996).
       0.625
H08_orf193
Conserved hypothetical protein; MPN454(new), 386(Himmelreich et al., 1996).
  
    0.592
hmw1
Cytadherence accessory protein HMW1; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity).
  
    0.533
G12_orf225
Putative membrane integrated oxidoreductase; MPN527(new), 315(Himmelreich et al., 1996).
   
  
 0.528
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
   
  
 0.522
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
       0.443
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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