STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ygl3Putative rRNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (166 aa)    
Predicted Functional Partners:
trmB
Methyltransferase-like protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.892
yceC
Ribosomal large subunit pseudouridine synthase D-like protein; MPN292(new), 544(Himmelreich et al., 1996).
  
  
 0.826
ileS
isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
  
    0.586
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
  
 0.577
VXpSPT7_orf112
Conserved hypothetical protein; MPN163(new), 669(Himmelreich et al., 1996).
   
  
 0.516
E07_orf140
Conserved hypothetical protein; MPN148(new), 007(Himmelreich et al., 1996); see: MPN643; Belongs to the MG439/MG440 family.
      
 0.504
G12_orf348
Conserved hypothetical protein; MPN518(new), 324(Himmelreich et al., 1996).
  
    0.484
H91_orf453
Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent).
     
 0.474
NadD
Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity.
  
  
 0.449
dyr
Dihydrofolate reductase; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity).
  
    0.448
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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