STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G12_orf269Conserved hypothetical protein; MPN552(new), 290(Himmelreich et al., 1996). (269 aa)    
Predicted Functional Partners:
thiI
Thiamin biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
    0.836
G12_orf281
Conserved hypothetical protein; MPN551(new), 291(Himmelreich et al., 1996).
  
    0.822
thrSv
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
    0.792
G12_orf326
Pseudouridine synthase; MPN548(new), 294(Himmelreich et al., 1996).
  
    0.787
G12_orf104
Conserved hypothetical protein; MPN554(new), 288(Himmelreich et al., 1996).
  
    0.787
H03_orf193o
Conserved hypothetical protein; MPN555(new), 287(Himmelreich et al., 1996).
  
    0.787
G12_orf325
Phosphodiesterase; MPN549(new), 293(Himmelreich et al., 1996); Belongs to the mgp1/MG371 family.
       0.773
G12_orf558
Dihydroacetone kinase; MPN547(new), 295(Himmelreich et al., 1996).
  
    0.717
argS
arginyl-tRNA synthetase; MPN556(new), 286(Himmelreich et al., 1996).
  
    0.702
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.668
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.