STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G12_orf104Conserved hypothetical protein; MPN554(new), 288(Himmelreich et al., 1996). (104 aa)    
Predicted Functional Partners:
thrSv
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
    0.842
H03_orf193o
Conserved hypothetical protein; MPN555(new), 287(Himmelreich et al., 1996).
  
    0.800
G12_orf269
Conserved hypothetical protein; MPN552(new), 290(Himmelreich et al., 1996).
  
    0.787
G12_orf326
Pseudouridine synthase; MPN548(new), 294(Himmelreich et al., 1996).
  
    0.780
thiI
Thiamin biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
    0.780
G12_orf281
Conserved hypothetical protein; MPN551(new), 291(Himmelreich et al., 1996).
  
    0.780
G12_orf325
Phosphodiesterase; MPN549(new), 293(Himmelreich et al., 1996); Belongs to the mgp1/MG371 family.
       0.773
G12_orf109
Bacterial histone-like protein; MPN529(new), 313(Himmelreich et al., 1996).
   
  
 0.734
argS
arginyl-tRNA synthetase; MPN556(new), 286(Himmelreich et al., 1996).
  
    0.661
smc
SMC family, chromosome/DNA binding/protecting functions; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
  
 0.645
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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