STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D02_orf129Conserved hypothetical protein; MPN570(new), 272(Himmelreich et al., 1996). (129 aa)    
Predicted Functional Partners:
LcnDR3
Hemolysin ABC-type exporter-like protein; MPN571(new), 271(Himmelreich et al., 1996).
  
  
 0.787
K05_orf345
Conserved hypothetical protein; MPN670(new), 172(Himmelreich et al., 1996).
      
 0.739
D02_orf346
Conserved hypothetical protein; MPN577(new), 265(Himmelreich et al., 1996); see: MPN083; Belongs to the MG067/MG068/MG395 family.
      
 0.656
D02_orf347
Conserved hypothetical protein; MPN586(new), 256(Himmelreich et al., 1996); see: MPN083; Belongs to the MG067/MG068/MG395 family.
      
 0.642
pepA
Cytosol aminopeptidase-like protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).
  
  
 0.636
D02_orf439
Conserved hypothetical protein; MPN582(new), 260(Himmelreich et al., 1996); see: MPN083.
      
 0.604
groEL
Heat shock protein GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.
  
    0.524
groES
Heat shock protein GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
    0.524
spg
Small GTPase ERA involved in regulating metabolism and cell division; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.514
ybeY
Predicted metalloenzyme interacting with hemolysin; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
       0.511
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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