STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_1180O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (302 aa)    
Predicted Functional Partners:
MYPU_1190
Conserved hypothetical protein; Identified by sequence similarity; putative; similar to TREMBL:O66494 (O66494) Blastp2 P=1e-06 C=50%.
  
 
 0.996
MYPU_1200
Conserved hypothetical protein; Identified by sequence similarity; possible; similar to SWISS-PROT:O52749 (YJEE_ANASP) Blastp2 P=1e-11 C=46% Pfscan: pos. 33-40 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop).
  
 
 0.986
MYPU_3470
PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (PHENYLALANINE--TRNA LIGASE BETA CHAIN) (PHERS); Identified by sequence similarity; possible; similar to SWISS-PROT:P75563 (SYFB_MYCPN) Blastp2 P=3e-43 C=46%; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.682
MYPU_1240
GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD+]; Identified by sequence similarity; possible; similar to SWISS-PROT:P46919 (GPDA_BACSU) Blastp2 P=2e-28 C=48%; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
      0.664
MYPU_7200
DNA POLYMERASE I (POL I); 5'-3' exonuclease acting preferentially on double-stranded DNA.
     
 0.637
MYPU_3480
Phenylalanine--tRNA ligase alpha subunit; Identified by sequence similarity; possible; similar to SWISS-PROT:P17921 (SYFA_BACSU) Blastp2 P=9e-58 C=57%; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
   
 0.572
MYPU_4710
DNA TOPOISOMERASE I (OMEGA-PROTEIN) (RELAXING ENZYME) (UNTWISTING ENZYME) (SWIVELASE); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...]
     
 0.556
MYPU_1210
Unknown; No similarity found.
       0.551
MYPU_0150
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.530
MYPU_4900
METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
     
 0.528
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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