STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_5500tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (282 aa)    
Predicted Functional Partners:
MYPU_2050
TRANSLATION INITIATION FACTOR IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
 0.978
MYPU_6720
RIBOSOME-BINDING FACTOR A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
  
 0.904
MYPU_2070
LIPOPROTEIN; No similarity found Pfscan: pos. 6-16 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site.
  
 
 0.901
MYPU_1660
Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 
 0.871
MYPU_5490
Conserved hypothetical protein; Identified by sequence similarity; putative; similar to SWISS-PROT:P42962 (YCSE_BACSU) Blastp2 P=1e-13 C=42% Pfscan: pos. 10-262 PF00592 | DUF3 Domain of Unknown Function 3.
  
    0.841
MYPU_2030
N-UTILIZATION SUBSTANCE PROTEIN A; Identified by sequence similarity; putative; similar to SWISS-PROT:P75591 (NUSA_MYCPN) Blastp2 P=2e-27 C=32%.
  
    0.814
MYPU_5480
RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF [INCLUDES: RIBOFLAVIN KINASE (FLAVOKINASE); Identified by sequence similarity; putative; similar to TREMBL:Q9WZW1 (Q9WZW1) Blastp2 P=2e-13 C=33%.
  
  
 0.802
MYPU_3060
GTP-BINDING PROTEIN; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
   
 
 0.800
MYPU_3280
30S RIBOSOMAL PROTEIN S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
 
 0.796
MYPU_5450
DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN) (RNA POLYMERASE BETA' SUBUNIT); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.775
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.