STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_6870GUANYLATE KINASE (GMP KINASE); Essential for recycling GMP and indirectly, cGMP. (196 aa)    
Predicted Functional Partners:
MYPU_3220
ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.966
MYPU_5510
HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (HGPRT) (HGPRTASE); Identified by sequence similarity; possible; similar to SWISS-PROT:P37472 (HPRT_BACSU) Blastp2 P=2e-38 C=61%; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.933
MYPU_2400
PYRUVATE KINASE (PK); Identified by sequence similarity; probable; similar to SWISS-PROT:P78031 (KPYK_MYCPN) Blastp2 P=7e-95 C=59%; Belongs to the pyruvate kinase family.
  
 
 0.924
MYPU_5410
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (RIBONUCLEOTIDE REDUCTASE); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.914
MYPU_5390
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN (RIBONUCLEOTIDE REDUCTASE); Identified by sequence similarity; probable; similar to SWISS-PROT:P75461 (RIR2_MYCPN) Blastp2 P=0 C=77%.
     
 0.910
MYPU_5670
ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 
 0.910
MYPU_0550
5'-NUCLEOTIDASE PRECURSOR; Identified by sequence similarity; putative; similar to SWISS-PROT:P22848 (5NTD_VIBPA) Blastp2 P=5e-36 C=42%; Belongs to the 5'-nucleotidase family.
    
  0.903
MYPU_5180
ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.898
MYPU_6860
PROTEIN PHOSPHATASE; Identified by sequence similarity; possible; similar to SWISS-PROT:P47354 (PPH_MYCGE) Blastp2 P=6e-23 C=53%.
   
   0.841
MYPU_6830
RIBULOSE-PHOSPHATE 3-EPIMERASE (PENTOSE-5-PHOSPHATE 3-EPIMERASE) (PPE) (R5P3E); Identified by sequence similarity; possible; similar to SWISS-PROT:Q9ZJ75 (RPE_HELPJ) Blastp2 P=9e-25 C=52%.
  
 
 0.827
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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