STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_7180PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (379 aa)    
Predicted Functional Partners:
MYPU_7200
DNA POLYMERASE I (POL I); 5'-3' exonuclease acting preferentially on double-stranded DNA.
  
    0.838
MYPU_7170
Predicted coding region; No similarity found.
       0.781
MYPU_7190
DNA POLYMERASE III, ALPHA CHAIN; Identified by sequence similarity; possible; similar to SWISS-PROT:O34623 (DP3A_BACSU) Blastp2 P=0 C=46%.
       0.776
MYPU_7210
Conserved hypothetical protein; Identified by sequence similarity; similar to TREMBL:O25502 Blastp2 P=2e-9 score=62.5 Pfscan: pos. 1-171 PF01121 | UPF0038 Uncharacterized protein family UPF0038 (PDOC00996) pos. 6-13 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); Belongs to the CoaE family.
       0.775
MYPU_5500
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
   
  
 0.691
MYPU_7220
Unknown; No similarity found.
       0.562
MYPU_7160
30S RIBOSOMAL PROTEIN S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
    0.553
MYPU_3470
PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (PHENYLALANINE--TRNA LIGASE BETA CHAIN) (PHERS); Identified by sequence similarity; possible; similar to SWISS-PROT:P75563 (SYFB_MYCPN) Blastp2 P=3e-43 C=46%; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.539
MYPU_7230
Unknown; No similarity found.
       0.528
MYPU_7150
Unknown; No similarity found.
       0.475
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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