STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_7780PEPTIDE METHIONINE SULFOXIDE REDUCTASE (PEPTIDE MET(O) REDUCTASE); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (177 aa)    
Predicted Functional Partners:
MYPU_0090
50S RIBOSOMAL PROTEIN L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.999
MYPU_5460
DNA-DIRECTED RNA POLYMERASE BETA CHAIN (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.999
MYPU_5060
PEPTIDE METHIONINE SULFOXIDE REDUCTASE (PEPTIDE MET(O) REDUCTASE); Identified by sequence similarity; probable; similar to SWISS-PROT:O25011 (PMSR_HELPY) Blastp2 P=1e-44 C=67%.
 
 0.994
MYPU_7610
DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF PYRUVATE COMPLEX); Identified by sequence similarity; possible; similar to SWISS-PROT:P47513 (DLDH_MYCGE) Blastp2 P=0 C=45%.
  
 0.993
MYPU_0210
DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF PYRUVATE COMPLEX); Identified by sequence similarity; possible; similar to SWISS-PROT:P47513 (DLDH_MYCGE) Blastp2 P=4e-74 C=53%.
  
 0.990
MYPU_7200
DNA POLYMERASE I (POL I); 5'-3' exonuclease acting preferentially on double-stranded DNA.
  
 
 0.965
MYPU_7130
THIOREDOXIN REDUCTASE; Identified by sequence similarity; probable; similar to SWISS-PROT:P80880 (TRXB_BACSU) Blastp2 P=4e-62 C=62%.
  
 
 0.961
MYPU_7330
HEAT SHOCK PROTEIN DNAJ (activation of DNAK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent intera [...]
   
 
 0.959
MYPU_2230
HEAT SHOCK PROTEIN DNAK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.942
MYPU_5690
50S RIBOSOMAL PROTEIN L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.942
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.