STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_0140Conserved hypothetical protein; Identified by sequence similarity; possible; similar to SWISS-PROT:P37545 (YABD_BACSU) Blastp2 P=7e-41 C=60% ScanProsite: PDOC00836 PS01090 UPF0006_2 Uncharacterized protein family UPF0006 signature 2 122-132 PVIIHCRETFD. (252 aa)    
Predicted Functional Partners:
MYPU_0150
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.944
MYPU_4900
METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
   0.824
MYPU_0160
Unknown; No similarity found.
       0.773
MYPU_0130
THIOPHENE AND FURAN OXIDATION PROTEIN THDF; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
    0.683
MYPU_6590
PROTEIN-EXPORT MEMBRANE PROTEIN SECD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
  
  
 0.573
MYPU_0120
Unknown; No similarity found.
       0.494
MYPU_0170
Glucose PTS system EIICBA or EIICB component; Identified by sequence similarity; putative; similar to SWISS-PROT:P20166 (PTGA_BACSU) Blastp2 P=9e-64 C=29% Pfscan: pos. 656-765 PF00358 | PTS_EIIA_1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PDO pos. 531-565 PF00367 | PTS_EIIB phosphotransferase system, EIIB (PDOC00795) pos. 686-738 GC0246 | PTS_EII_EIII_1 PTS EII/EIII components phosphorylation site sig pos. 706-718 PS00371 | PTS_EIIA_1 PTS EIIA domains phosphorylation site signature 1.
       0.470
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.