Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAB0249ABC ABC-type transport system, ATPase component, substrate unknown; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity). (280 aa)    
Predicted Functional Partners:
PAB2261
Cobalt transport protein, cbiQ family.
 
 0.992
PAB2248
bioY biotin biosynthesis protein.
 
 
 0.953
trkH
trkG/H trk potassium uptake system protein.
  
  
 0.937
PAB2260
ABC transporter, ATP-binding protein, substrate unknown; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
  
 
 
0.830
map
Map methionine aminopeptidase (EC 3.4.11.18); Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
  
  
 0.732
tiaS
Predicted DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
       0.638
PAB2090
Hypothetical protein.
 
 
 
 0.632
truA
truA pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
  
 0.622
PAB1929
ABC transporter, ATP-binding protein, putative.
  
  
 
0.563
PAB2232
Sugar transport, ABC transporter ATP-binding protein.
  
  
 
0.560
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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