Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ksgAksgA dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (269 aa)    
Predicted Functional Partners:
PAB0252
Predicted RNA-binding protein.
     
 0.941
nob1
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family.
   
 
 0.939
rps6e
rps6E SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 
 0.914
rpl21E
rpl21E LSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family.
  
  
 0.905
rps19e
rps19E SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.903
rps17e
rps17E SSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family.
   
 
 0.901
nep1
Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA (By similarity).
  
 
 0.898
rps5
rps5P SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
 
 
 0.883
PAB0406
Predicted RNA-binding protein.
  
 
 0.881
rps4P
rps4P SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.880
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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