node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAB1056 | ogt | PAB1056 | PAB0260 | Haloacid dehalogenase-like hydrolase, NagD protein homolog. | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.466 |
PAB1103 | PAB1530 | PAB1103 | PAB1530 | Endonuclease IV. | alkA 3-methyladenine DNA glycosylase. | 0.674 |
PAB1103 | nth | PAB1103 | PAB0459 | Endonuclease IV. | Nth endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.854 |
PAB1103 | ogt | PAB1103 | PAB0260 | Endonuclease IV. | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.467 |
PAB1108 | ogt | PAB1108 | PAB0260 | Universal stress DNA-binding protein, UspA. | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.554 |
PAB1530 | PAB1103 | PAB1530 | PAB1103 | alkA 3-methyladenine DNA glycosylase. | Endonuclease IV. | 0.674 |
PAB1530 | nth | PAB1530 | PAB0459 | alkA 3-methyladenine DNA glycosylase. | Nth endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.608 |
PAB1530 | ogt | PAB1530 | PAB0260 | alkA 3-methyladenine DNA glycosylase. | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.743 |
PAB2090 | PAB2408 | PAB2090 | PAB2408 | Hypothetical protein. | TRP-repeat-containing protein. | 0.566 |
PAB2090 | ogt | PAB2090 | PAB0260 | Hypothetical protein. | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.627 |
PAB2090 | thiL | PAB2090 | PAB2358 | Hypothetical protein. | thiL thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.566 |
PAB2408 | PAB2090 | PAB2408 | PAB2090 | TRP-repeat-containing protein. | Hypothetical protein. | 0.566 |
PAB2408 | ogt | PAB2408 | PAB0260 | TRP-repeat-containing protein. | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.860 |
PAB2408 | thiL | PAB2408 | PAB2358 | TRP-repeat-containing protein. | thiL thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.788 |
nth | PAB1103 | PAB0459 | PAB1103 | Nth endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Endonuclease IV. | 0.854 |
nth | PAB1530 | PAB0459 | PAB1530 | Nth endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | alkA 3-methyladenine DNA glycosylase. | 0.608 |
nth | ogt | PAB0459 | PAB0260 | Nth endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.511 |
ogt | PAB1056 | PAB0260 | PAB1056 | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Haloacid dehalogenase-like hydrolase, NagD protein homolog. | 0.466 |
ogt | PAB1103 | PAB0260 | PAB1103 | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Endonuclease IV. | 0.467 |
ogt | PAB1108 | PAB0260 | PAB1108 | Ogt 6-O-methylguanine-DNA methyltransferase (EC 2.1.1.63); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Universal stress DNA-binding protein, UspA. | 0.554 |