Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
eno-likeEno-like enolase related. (342 aa)    
Predicted Functional Partners:
PAB1441
Pyk pyruvate kinase (EC 2.7.1.40) (PK); Belongs to the pyruvate kinase family.
 
 0.998
rps2P
rps2P SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.981
pgk
Pgk 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 
 0.977
rps9P
rps9P SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.971
rpoK
rpoK DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
  
  
 0.971
PAB1021
Putative hydroxypyruvate reductase.
    
 0.967
gap
Gap glyceraldehyde 3-phosphate dehydrogenase.
  
 
 0.960
tpiA
tpiA triosephosphate isomerase, archaeal triose phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.958
rps4P
rps4P SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
 0.944
apgM
Probable phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.939
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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