Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAB0502Hypothetical protein. (284 aa)    
Predicted Functional Partners:
PAB0503
Hypothetical protein.
       0.933
PAB0504
Hypothetical protein.
       0.933
crcB
Chromosome condensation protein, crcB homolog; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.734
PAB1926
Hypothetical protein; Belongs to the UPF0166 family.
       0.717
PAB2114
Metallopeptidase-2.
       0.717
trm5b
Hypothetical protein, Met-10+ like protein; Specifically methylates the N1 position of guanosine-37 in various tRNAs.
       0.688
dfp
Dfp DNA/pantothenate metabolism flavoprotein.
       0.636
PAB2394
Haloacid dehalogenase-like hydrolase, putative; Catalyzes the dephosphorylation of 2-phosphoglycolate.
       0.491
PAB1981
Glycosyltransferase.
       0.480
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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