Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAB0737Hypothetical protein, containing vinyl 4 reductase domain. (399 aa)    
Predicted Functional Partners:
rpl7AE
rpl7AE LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
       0.590
PAB0736
Hypothetical protein.
       0.578
rps28E
rps28E SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family.
       0.494
rpl24E
rpl24E LSU ribosomal protein L24E; Binds to the 23S rRNA.
       0.494
PAB1633
Hypothetical protein, containing KH nucleic acid binding domain.
     
 0.445
PAB0161
Hypothetical protein, containing archaeal Zn-finger.
       0.432
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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