Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
eif2bTranslation initiation factor eIF-2, beta subunit, putative; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family. (140 aa)    
Predicted Functional Partners:
eif2g
eIF2G translation initiation factor eIF-2, subunit gamma (eIF2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
 0.999
aif2A
eIF2A translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
  
 0.998
aif1A
eIF1A translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
 
 0.998
rps4e
rps4E SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.980
rps3AE
rps3AE SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.
 
 0.970
rps15P
rps15P SSU ribosomal protein S15P.
  
 0.969
rps6e
rps6E SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.969
rps3
rps3P SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 0.962
rps5
rps5P SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 0.957
rps12P
rps12P SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 0.955
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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