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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppaPpa thermostable inorganic pyrophosphatase (EC 3.6.1.1) (pyrophosphate phospho-hydrolase) (PPASE); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (178 aa)    
Predicted Functional Partners:
PAB1181
atpK archaeal/vacuolar-type H+-ATPase subunit K.
  
 
 0.967
atpD
atpD archaeal/vacuolar-type H+-transporting ATP synthase, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
  0.945
atpB
atpB archaeal/vacuolar-type H+-transporting ATP synthase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
   
 
 0.938
atpA
atpA intein containing archaeal/vacuolar-type H+-transporting ATP synthase, subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family.
   
 
 0.936
atpI
atpI archaeal/vacuolar-type H+-ATPase subunit I; Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.919
atpE
atpE archaeal/vacuolar-type H+-transporting ATP synthase, subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.913
atpF
atpF archaeal/vacuolar-type H+-transporting ATP synthase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
  0.909
eif5a
Translation initiation factor eIF5A (hypusine containing); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
   
  
 0.908
PAB1179
atpH archaeal/vacuolar-type H+-ATPase subunit H.
     
  0.900
atpC
atpC archaeal/vacuolar-type H+-transporting ATP synthase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
     
  0.900
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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