Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAB1674lysC like1 aspartate kinase related. (368 aa)    
Predicted Functional Partners:
asd
Asd aspartate-semialdehyde dehydrogenase.
 
 
 0.998
lysC
lysC like2 aspartate kinase related.
 
  
 
0.965
hom
Hom homoserine dehydrogenase.
 
 0.963
thrB
Hk homoserine kinase (EC 2.7.1.39); Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 
 0.950
asnB
Asparagine synthase (glutamine-hydrolyzing) (EC 6.3.5.4).
 
 
 0.891
thrC-2
thrC threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.889
aspB-2
aspC-2 aspartate aminotransferase (EC 2.6.1.1).
 
 
 0.888
PAB1605
Putative putative asparagine synthetase (glutamine-hydrolyzing) (EC 6.3.5.4).
  
 
 0.868
purA
purA adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.834
pyrI
pyrI aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
 
  
  0.825
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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