Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAB1968ADP-ribose pyrophosphatase (nudix family) (EC 3.6.1.13). (173 aa)    
Predicted Functional Partners:
PAB1967
Carbohydrate kinase, PfkB family.
     
 0.906
PAB1318
nadM nicotinamide nucleotide adenylyltransferase.
   
 0.861
PAB1927
Hypothetical protein.
       0.717
imp1
Imp1 hypothetical myo-inositol monophosphosphatase.
 
  
 0.716
PAB3084
Hypothetical protein.
       0.594
PAB0209
Uncharacterized phosphoesterase.
     
 0.575
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Regulates activity of NucS endonuclease and prevents non- specific cleavage.
     
 0.568
apbA
panE 2-dehydropantoate reductase (EC 1.1.1.169); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
      0.566
PAB2291
Hypothetical protein; Belongs to the UPF0215 family.
 
     0.528
PAB1464
Tfs archaeal transcription factor S; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
       0.511
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.