Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAB1972Hypothetical protein. (118 aa)    
Predicted Functional Partners:
PAB1971
Glycosyltransferase.
     
 0.935
PAB1288
GNPTA UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GTP) (G1PT) (N-acetylglucosamine-1-phosphate transferase) (GLCNAC-1-P transferase).
     
 0.722
PAB2312
Transcriptional regulatory protein Lrp-Asn family.
       0.680
PAB1973
Hypothetical protein.
       0.643
htpX-2
Heat shock protein/ Zn-dependent protease with chaperone function, M48 family.
       0.642
tyrS
tyrS tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
       0.630
prf1
Prf1 peptide chain release factor subunit 1 (translation termination factor ARF1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
       0.563
PAB1975
dCMP deaminase, putative.
       0.536
pfpI
pfpI intracellular protease. protease I; Deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation [...]
       0.512
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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