Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAB2000Hypothetical protein. (370 aa)    
Predicted Functional Partners:
wlbD
wlbD UDP-N-acetylglucosamine 2-epimerase.
 
    0.866
PAB0378
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.709
PAB0564
Predicted protein kinase, putative.
  
     0.609
priS
DNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own, synthesizing DNA strands up to 3 kB. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability for RNA fragments up to 150 bases. The DNA polymerase activity may enable DNA primase t [...]
  
     0.535
PAB0776
GDP-mannose or UDP-glucose6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.506
PAB0953
Hypothetical protein, containing cell wall binding repeat 2.
  
    0.499
PAB2141
Membrane protein, putative.
  
     0.490
PAB1586
Oligosaccharyl transferase, STT3 subunit.
  
     0.471
PAB2357
Component of the U3 small nucleolar ribonucleoprotein, imp4 homolog; Probably involved in the biogenesis of the ribosome.
  
     0.469
nusA-2
Hypothetical protein, containing KH nucleic acid binding domain.
  
     0.446
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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