Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAB2010eriC voltage gated chloride channel. (379 aa)    
Predicted Functional Partners:
PAB0431
Hypothetical protein.
       0.717
PAB1705
Hypothetical protein.
       0.717
thiL
thiL thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.717
PAB0828
Polysaccharide deacetylase, putative.
       0.610
PAB1859
Act-like pyruvate formate-lyase activating enzyme related protein.
       0.602
PAB1860
Hypothetical protein.
       0.602
PAB2009
Hypothetical protein.
       0.586
PAB1527
Probable Na+/alanine transport protein.
  
    0.547
PAB0826
Integral membrane protein.
       0.541
PAB0359
Ribosomal RNA small subunit methyltransferase C (rRNA (guanine-n2-)-methyltransferase) (16S rRNA M2G1207 methyltransferase).
     
 0.471
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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