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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkCPfk ADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (451 aa)    
Predicted Functional Partners:
pgiA
Glucose-6-phosphate isomerase.
    
 0.919
glkA
ADP-dependent glucokinase; Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
  
  
0.918
tkt1
Tkt1 transketolase N-terminal section.
  
  
  0.915
fba
Archaeal fructose 1,6-bisphosphate aldolase class 1A; Belongs to the DeoC/FbaB aldolase family.
    
 0.913
fbp-2
Fbp fructose 1,6-bisphosphatase (EC 3.1.3.11); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
 0.908
pmm
PMM phosphomannomutase.
    
 0.904
tkt2
Tkt2 transketolase C-terminal section.
     
  0.900
hps
Hps D-arabino 3-hexulose 6-phosphate formaldehyde lyase.
     
  0.900
PAB1021
Putative hydroxypyruvate reductase.
     
 0.816
PAB0645
Sugar-phosphate nucleotidyl transferase.
    
 
 0.655
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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