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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smcSmc1 chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1177 aa)    
Predicted Functional Partners:
PAB2110
Hypothetical protein.
 
 
 0.999
PAB2162
Transcriptional regulator, putative (ypuH-like).
 
 
 0.976
minD-2
minD-2 ATPase involved in chromosome partitioning, minD/MRP superfamily.
     
 0.877
soj
ATPase involved in chromosome partitioning, minD/MRP superfamily.
  
  
 0.690
srp54
Srp54 signal recognition particle, subunit SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
 
 0.648
infB
infB intein containing translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
 
  
 0.648
PAB0241
Probable protease, caaX family.
 
   
 0.641
PAB0240
Putative effector of murein hydrolase.
  
  
 0.630
PAB0190
Putative ATP-dependent ERCC4-like helicase.
  
 
 0.629
PAB0764
Histone deacetylase.
   
 0.611
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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